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|Trade names||Prograf, Advagraf, Protopic, others|
|License data||EU EMA: by INN|
|Pregnancy category||AU: C US: C (Risk not ruled out)|
|Routes of administration||Topical, oral, iv|
|ATC code||D11AH01 ( WHO ) L04AD02 ( WHO )|
|Legal status||In general: ℞ (Prescription only)|
|Bioavailability||24% (5–67%), less after eating food rich in fat|
|Metabolism||Hepatic CYP3A4, CYP3A5|
|Elimination half-life||11.3 h for transplant patients (range 3.5–40.6 h)|
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|Prograf other names||protopic, protopic, protopic, protopic|
|Active substance||tacrolimus, tacrolimus|
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